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Role of gene polymorphisms of proinflammantory cytokines IL-1 in primary knee and hip osteoarthritis

Objectives. Osteoarthritis (OA) is a frequent joint disease with complex genetic risk. Genetic predisposition to the complex hereditary disease like OA of the large joints (hip and knee) includes the interleukin-1 gene (IL1) cluster on chromosome 2. Also, one of the loci that could predispose the development of OA is located on chromosome 6 (6p12.3-q13). Near this locus is a gene, which encodes th…

Вижте на уебсайта на доставчик на данни (отваря се в нов прозорец)

Сътрудници

  • Dembić, Zlatko
  • Šestan, Branko

Създател

  • Jotanović, Zdravko

Издател

  • University of Rijeka. Faculty of Medicine.

Тема

  • BIOMEDICINE AND HEALTHCARE. Basic Medical Sciences.
  • General genetics. General cytogenetics
  • Genetic Predisposition to Disease
  • Interleukins
  • Interleukin-1
  • Interleukin-17
  • Osteoarthritis
  • Hip
  • Knee
  • Single Nucleotide Polymorphism

Вид на обекта

  • info:eu-repo/semantics/doctoralThesis
  • text

Дата

  • 2013-03-14
  • 2013-03-14