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Effect of genetic variants of the ABCC2 transporter on bioavailability of mycophenolic acid in renal-transplant patients
Mycophenolic acid (MPA) displays variable pharmacokinetics (PK). It is metabolized by UGTs to MPA-glucuronide which is subject to enterohepatic recirculation. Biliary and kidney excretion involves multidrug resistant protein 2 (MRP2) coded by ABCC2. We assessed steady-state PK of MPA in renal allograft recipients in respect to donor and recipient ABCC2 genotypes, along with other clinical covariat…
Myötävaikuttajat
- Božina, Nada
Luoja
- Lalić, Zdenka
Julkaisija
- University of Zagreb. Faculty of Pharmacy and Biochemistry.
Aihe
- BIOMEDICINE AND HEALTHCARE. Pharmacy. Pharmacy.
- Biotechnology. Genetic engineering. Products of cloning
- mycophenolic acid
- pharmacokinetics
- pharmacogenetics
- MRP2/ABCC2
- renal transplant patients
- cyclosporine
- tacrolimus
Aineisto tyyppi
- info:eu-repo/semantics/doctoralThesis
- text
Päivämäärä
- 2015-12-03
- 2015-12-03
Myötävaikuttajat
- Božina, Nada
Luoja
- Lalić, Zdenka
Julkaisija
- University of Zagreb. Faculty of Pharmacy and Biochemistry.
Aihe
- BIOMEDICINE AND HEALTHCARE. Pharmacy. Pharmacy.
- Biotechnology. Genetic engineering. Products of cloning
- mycophenolic acid
- pharmacokinetics
- pharmacogenetics
- MRP2/ABCC2
- renal transplant patients
- cyclosporine
- tacrolimus
Aineisto tyyppi
- info:eu-repo/semantics/doctoralThesis
- text
Päivämäärä
- 2015-12-03
- 2015-12-03
Aineiston tarjoaja
Aggregaattori
Tämän aineisto median lisenssi (ellei toisin mainita)
- http://rightsstatements.org/vocab/InC/1.0/
Tunniste
- https://dr.nsk.hr/islandora/object/pharma:263
- https://urn.nsk.hr/urn:nbn:hr:163:726121
- https://repozitorij.unizg.hr/islandora/object/pharma:263
- https://dr.nsk.hr/islandora/object/pharma%3A263/datastream/TN/view/
Muoto
- application/pdf
Kieli
- hrv
Alkuperämaa
- Croatia
Kokoelman nimi
Julkaistu ensimmäistä kertaa Europeana
- 2019-04-05T13:44:11.531Z
Viimeksi päivitetty aineiston tarjoajalta
- 2019-04-05T13:44:11.531Z