Uloga adhezijskih molekula ICAM-1 i VCAM-1 u nastajanju psorijaze : doktorska disertacija

Introduction
Psoriasis vulgaris is a systemic Th1 cytokine-mediated skin disease. In psoriatic
epidermis, the leading change is proliferation of keratinocytes associated with
inflammation. The role of immunologic reactions is obvious through the presence of
many activated T lymphocytes in epidermis and dermis and also association with
HLA class I antigen. Stimulation of T lymphocytes in epide…