Virusna regulacija aktivnosti NK-limfocita: uloga inhibicijskih LY49 receptora : doktorski rad

Objectives
Regulation of NK cell response in acute mouse cytomegalovirus (MCMV) infection is dependent
on the fine balance of signals coming from activating and inhibitory receptors expressed on their
cell surface. In order to sidestep antigen presentation and recognition by CD8+T cells, MCMV
encodes immunoevasion proteins that downmodulate the expression of MHC class I on the
surface of infe…